From membranoproliferative glomerulonephritis to a final diagnosis: Hypocomplementemic urticarial vasculitis syndrome

Membranoproliferative glomerulonephritis describes a glomerular-injury pattern common to heterogeneous group of diseases. Evaluation based on clinical and laboratory presentation immunofluorescence staining kidney biopsy allows identification underlying pathophysiological processes may facilitate proper diagnosis treatment. Hypocomplementemic urticarial vasculitis syndrome is rare autoimmune disease multi-organ involvement. The well-defined criteria. pathophysiology not completely understood but the presence anti-C1q antibody seems be involved. Renal involvement occurs in up 50% cases. It can indistinguishable from lupus nephritis. Serological findings skin distinguish these two entities. We report case 40-year-old female who presented with lesions, hypocomplementemia nephrotic syndrome. Kidney showed membranoproliferative full house immune complex deposits. hypocomplementemic was made patient successfully treated prednisolone mycophenolate mofetil.